Infect Chemother.  2010 Apr;42(2):127-131.

A Case of Acute Pulmonary Thromboembolism Complicated Pandemic Influenza (H1N1 2009)

• Lee JH
• Kim M
• Lee J
• Kim J
• Shin SY

Abstract

During the pandemic, few patients have suffered from severe pneumonia leading to acute respiratory distress syndrome (ARDS) and multiple organ dysfunction necessitating prolonged intensive care with higher mortality. Although sepsis and ARDS represent hypercoagulable states, acute pulmonary thromboembolism is rarely encountered in influenza infection. Fifty five year old female patient admitted with pneumonia associated with influenza A infection, progressed into ARDS. Pulmonary thromboembolism was detected by CT scan and treated with anticoagulants. This is the first case report of acute pulmonary thromboembolism in a patient with pandemic influenza (H1N1 2009) in Korea.

Keyword

Pulmonary thromboembolism; Influenza A virus; Respiratory distress syndrome; Peramivir

MeSH Terms

Anticoagulants
Critical Care
Cyclopentanes
Female
Guanidines
Humans
Influenza A virus
Influenza, Human
Korea
Pandemics
Pneumonia
Pulmonary Embolism
Respiratory Distress Syndrome, Adult
Sepsis
Anticoagulants
Cyclopentanes
Guanidines

Figure

• 

  Figure 1 (A) Chest radiograph (admission day 1) shows bilateral pulmonary infiltrates. (B) High resolution CT shows multiple ground-glass attenuations and consolidation on the both lung fields.

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  Figure 2 (A) Chest CT (admission day 6) shows huge thrombus in the both main pulmonary artery. Thrombus extended to branches of left lower lobar artery. (B) Extensive ground-glass attenuations and consolidations in both lungs. CT findings shows deterioration of lesions comparing to previous chest CT.

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  Figure 3 (A) Chest CT after anticoagulation therapy (admission day 24) shows small residual thrombus in both main pulmonary artery. (B) Decreased extent of ground-glass attenuations and consolidations in both lungs.

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