Cancer Res Treat.  2018 Jan;50(1):40-49. 10.4143/crt.2016.594.

Development and Validation of the Korean Version of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire for Patients with Non-muscle Invasive Bladder Cancer: EORTC QLQ-NMIBC24

  • 1Department of Urology, Eulji University Hospital, Eulji University School of Medicine, Daejeon, Korea.
  • 2Department of Family Medicine, Seoul National University Hospital, Seoul, Korea.
  • 3Department of Urology, Kyungpook National University School of Medicine, Daegu, Korea.
  • 4Department of Urology, Chonnam National University Medical School, Gwangju, Korea.
  • 5Department of Urology, Pusan National University Yangsan Hospital, Yangsan, Korea.
  • 6Department of Urology, Wonkwang University School of Medicine, Iksan, Korea.
  • 7Department of Urology, Dankook University College of Medicine, Cheonan, Korea.
  • 8Department of Urology, Yonsei University Wonju College of Medicine, Wonju, Korea.
  • 9Department of Urology, Konyang University College of Medicine, Daejeon, Korea.
  • 10Department of Urology, Chungbuk National University College of Medicine, Cheongju, Korea.


We aimed to evaluate psychometric properties of the Korean version of the European Organization for Research and Treatment of Cancer (EORTC) QLQ-NMIBC24 when applied to Korean non-muscle invasive bladder cancer (NMIBC) patients.
A total of 249 patients who underwent curative transurethral resection of bladder tumor (TURBT) for primary or recurrent NMIBC were asked to complete the Korean version of EORTC QLQ-C30 and -NMIBC24 questionnaires three times (preoperative, post-TURBT 3 months and 6 months). Linguistic validation and psychometric evaluation of the questionnaire was conducted.
Multitrait scaling analysis confirmed satisfactory construct validity in five scales except the malaise scale. Internal consistency was good (Cronbach's alpha ≥ 0.70) for the five scales except the malaise scale at the all three time points. Known-group comparison analyses showed better quality-of-life (QOL) scores in patients with higher performance status as expected, and better sexual function in men than women (p < 0.05). Most of the scales had low correlations (< 0.40) with the scales in QLQ-C30 showing divergent validity, except for malaise scale which showed higher correlations (0.42 to 0.60). Responsiveness to change was consistent with clinical implications over time after TURBT.
The Korean version of the EORTC QLQ-NMIBC24 has good reliability and cross-cultural validity for measuring various QOL aspects that can be self-administered to Korean NMIBC patients undergoing TURBT.


Urinary bladder neoplasms; Psychometric properties; Quality of life; Surveys and questionnaire
Full Text Links
  • CRT
export Copy
  • Twitter
  • Facebook
Similar articles
Copyright © 2021 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: