Intest Res.  2018 Jan;16(1):160-162. 10.5217/ir.2018.16.1.160.

T-cell immune response against cytomegalovirus in peripheral blood and colonic mucosa from ulcerative colitis and Crohn's disease patients

• Nam SJ
• Kim ES
• Jeen YT

• KMID: 2402663
• DOI: http://doi.org/10.5217/ir.2018.16.1.160

Abstract

No abstract available.

MeSH Terms

Colitis, Ulcerative*
Colon*
Crohn Disease*
Cytomegalovirus*
Humans
Mucous Membrane*
T-Lymphocytes*
Ulcer*

Figure

• 

  Fig. 1 CD4 or CD8 cytokine production (interferon-γ [IFN-γ] and interleukin 4 [IL-4]) in response to cytomegalovirus (CMV) antigen or CD3/CD28 stimulation of UC, CD and healthy donor peripheral blood mononuclear cell. (A) IFN-γ production against CMV was lower in UC and CD patients than in healthy donors. (B) IFN-γ production after CD3/CD28 stimulation was comparable among the 3 groups. (C) IL-4 production against CMV was higher in UC patients than in the other groups. (D) IL-4 production from both CD4 and CD8 T-cells after CD3/CD28 stimulation was higher in CD patients than in the other groups.

Reference

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