Pediatr Infect Vaccine.  2017 Dec;24(3):188-192. 10.14776/piv.2017.24.3.188.

Respiratory Syncytial Virus Infection Complicated by Extrapulmonary Manifestations

• Jung JH
• Kim YK
• Choi HJ

• KMID: 2401395
• DOI: http://doi.org/10.14776/piv.2017.24.3.188

Abstract

Respiratory syncytial virus (RSV) typically causes lower respiratory tract infections in children, and most patients recover successfully. However, some infants and young children can have a severe course of disease with respiratory failure, and extrapulmonary manifestations can occur in severe RSV disease. We report one case of severe RSV bronchiolitis complicated with acute myocarditis, fulminant hepatic failure, and disseminated intravascular coagulation.

Keyword

Respiratory syncytial viruses; Myocarditis; Liver failure

MeSH Terms

Bronchiolitis
Child
Disseminated Intravascular Coagulation
Humans
Infant
Liver Failure
Liver Failure, Acute
Myocarditis
Respiratory Insufficiency
Respiratory Syncytial Viruses*
Respiratory Tract Infections

Figure

• 

  Figure 1 (A) Chest X-ray before admission shows the disparity of inspiration between left and right lungs. (B) Chest X-ray at admission day shows hyperinflation in both lungs and haziness in left lung.

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  Figure 2 (A) Cardiac enzymes including N-terminal pro-B-type natriuretic peptide (NT-proBNP) and troponin I rapidly decreased after intravenous immunoglobulin administration on admission day. (B) Liver enzymes including aspartate aminotransferase (AST), alanine aminotransferase (ALT), total bilirubin (t-Bil), and direct bilirubin (d-Bil) peaked at admission day 2 to 5 and then gradually decreased. Abbreviations: HD, hospital day; OPD, outpatient department.

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