Ann Dermatol.  2018 Feb;30(1):125-127. 10.5021/ad.2018.30.1.125.

Elephantiasic Graves' Dermopathy in a Patient with Negative Thyroid-Receptor Auto-Antibodies

• Berglund A
• Riis JL
• Krarup NH
• Spaun E
• Ebbehøj E

• KMID: 2399777
• DOI: http://doi.org/10.5021/ad.2018.30.1.125

Abstract

No abstract available.

MeSH Terms

Humans

Figure

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  Fig. 1 (A~C) Elephantiasic skin changes on the dorsal sides of the feet and legs consisting of pachydermal hyperkeratosis and a papillomatous cobblestone appearance with malodourous scattered impetiginized crusted wounds and fissures.

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  Fig. 2 Histopathology. (A) Punch biopsy from lower leg, showing papillary epidermal hyperplasia, slight inconspicuous vascular proliferation and edema (H&E, ×20). (B) Higher magnification. Inconspicuous vascular pattern (H&E, ×40). (C) Increased amount of mucin in papillary and reticular dermis (Colloidal iron stain, ×20). (D) Higher magnification showing the distribution of mucin in dermis (Colloidal iron stain, ×100).

Reference

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