Infect Chemother.  2017 Dec;49(4):286-292. 10.3947/ic.2017.49.4.286.

Infective Endocarditis Presenting as Endogenous Endophthalmitis Secondary to Streptococcus agalactiae in a Healthy Adult: Case Report and Literature Review

Affiliations
  • 1Division of Infectious Diseases, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea. young7912@korea.ac.kr
  • 2Department of Ophthalmology, Korea University College of Medicine, Seoul, Korea.

Abstract

Endogenous endophthalmitis secondary to group B Streptococcus (GBS) is extremely rare, particularly in healthy adults. However, the visual prognosis is poor. We report the first South Korean case of GBS infective endocarditis presenting as endogenous endophthalmitis and skin and soft tissue infection. Cultures of blood, vitreous humor, and pus from skin aspirates yielded a penicillin-susceptible serotype V strain of Streptococcus agalactiae. After 6 weeks, the patient completely recovered from GBS infective endocarditis. However, despite early antibiotic treatment and early surgical intervention, the patient's right eye developed phthisis bulbi and was a candidate for evisceration.

Keyword

Streptococcus agalactiae; Endophthalmitis; Endocarditis

MeSH Terms

Adult*
Endocarditis*
Endophthalmitis*
Humans
Patient Rights
Prognosis
Serogroup
Skin
Soft Tissue Infections
Streptococcus agalactiae*
Streptococcus*
Suppuration
Vitreous Body

Reference

1. Skoff TH, Farley MM, Petit S, Craig AS, Schaffner W, Gershman K, Harrison LH, Lynfield R, Mohle-Boetani J, Zansky S, Albanese BA, Stefonek K, Zell ER, Jackson D, Thompson T, Schrag SJ. Increasing burden of invasive group B streptococcal disease in nonpregnant adults, 1990-2007. Clin Infect Dis. 2009; 49:85–92.
Article
2. Lee SY, Chee SP, Group B. Streptococcus endogenous endophthalmitis: case reports and review of the literature. Ophthalmology. 2002; 109:1879–1886.
3. Farber BP, Weinbaum DL, Dummer JS. Metastatic bacterial endophthalmitis. Arch Intern Med. 1985; 145:62–64.
Article
4. Buglass TD, Romanchuk KG. Fatal case of group B streptococcal endogenous endophthalmitis. Can J Ophthalmol. 1995; 30:149–150.
5. The Korean Society of Infectious Diseases, Korean Society for Chemotherapy, The Korean Society of Clinical Microbiology, The Korean Society of Cardiology, The Korean Society for Thoracic and Cardiovascular Surgery. Clinical guideline for the diagnosis and treatment of cardiovascular infections. Infect Chemother. 2011; 43:129–177.
6. Schiedler V, Scott IU, Flynn HW Jr, Davis JL, Benz MS, Miller D. Culture-proven endogenous endophthalmitis: clinical features and visual acuity outcomes. Am J Ophthalmol. 2004; 137:725–731.
Article
7. Okada AA, Johnson RP, Liles WC, D'Amico DJ, Baker AS. Endogenous bacterial endophthalmitis. Report of a ten-year retrospective study. Ophthalmology. 1994; 101:832–838.
8. Sambola A, Miro JM, Tornos MP, Almirante B, Moreno-Torrico A, Gurgui M, Martinez E, Del Rio A, Azqueta M, Marco F, Gatell JM. Streptococcus agalactiae infective endocarditis: analysis of 30 cases and review of the literature, 1962-1998. Clin Infect Dis. 2002; 34:1576–1584.
Article
9. Matsuo K, Nakatuka K, Yano Y, Fujishima W, Kashima K. Group B streptococcal metastatic endophthalmitis in an elderly man without predisposing illness. Jpn J Ophthalmol. 1998; 42:304–307.
Article
10. O'Brart DP, Eykyn SJ. Septicaemic infection with group B streptococci presenting with endophthalmitis in adults. Eye (Lond). 1992; 6:396–399.
11. Wu Z, Huang J, Huynh S, Sadda S. Bilateral endogenous endophthalmitis secondary to group B streptococcal sepsis. Chin Med J (Engl). 2014; 127:1999.
12. Galloway A, Deighton CM, Deady J, Marticorena IF, Efstratiou A. Type V group B streptococcal septicaemia with bilateral endophthalmitis and septic arthritis. Lancet. 1993; 341:960–961.
Article
13. Ing EB, Erasmus MJ, Chisholm LD. Metastatic group B streptococcal endophthalmitis from a cutaneous foot ulcer. Can J Ophthalmol. 1993; 28:238–240.
14. Nagelberg HP, Petashnick DE, To KW, Woodcome HA Jr. Group B streptococcal metastatic endophthalmitis. Am J Ophthalmol. 1994; 117:498–500.
Article
15. Pokharel D, Doan AP, Lee AG. Group B streptococcus endogenous endophthalmitis presenting as septic arthritis and a homonymous hemianopsia due to embolic stroke. Am J Ophthalmol. 2004; 138:300–302.
Article
16. Gupta SR, Agnani S, Tehrani S, Yeh S, Lauer AK, Suhler EB. Endogenous Streptococcus agalactiae (Group B Streptococcus) endophthalmitis as a presenting sign of precursor T-cell lymphoblastic leukemia. Arch Ophthalmol. 2010; 128:384–385.
Article
17. Saffra N, Rakhamimov A, Husney R, Ghitan M. Streptococcus agalactiae endogenous endophthalmitis. BMJ Case Rep. 2013; 2013:pii:bcr2013008981.
18. Siddiqui MA, Lester RM. Septic arthritis and bilateral endogenousendophthalmitis associated with percutaneous transluminal coronary angioplasty. J Am Geriatr Soc. 1996; 44:476–477.
Article
19. Jackson TL, Eykyn SJ, Graham EM, Stanford MR. Endogenous bacterial endophthalmitis: a 17-year prospective series and review of 267 reported cases. Surv Ophthalmol. 2003; 48:403–423.
Article
20. Edwards MS, Baker CJ. Group B streptococcal infections in elderly adults. Clin Infect Dis. 2005; 41:839–847.
Article
Full Text Links
  • IC
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr