Korean J Otorhinolaryngol-Head Neck Surg.  2017 Nov;60(11):579-583. 10.3342/kjorl-hns.2016.16992.

A Case of Mucosa-Associated Lymphoid Tissue Lymphoma in Nasopharynx and Thyroid Gland

• Park WS
• Ko SH
• Yoo BJ
• Chung JH

• KMID: 2396866
• DOI: http://doi.org/10.3342/kjorl-hns.2016.16992

Abstract

Mucosa associated lymphoid tissue (MALT) lymphoma refers to a type of marginal zone lymphomas, which represent a group of non-Hodgkin lymphomas originated from B lymphocytes of marginal zone. They are classified as extranodal MALT type (MALT lymphoma), splenic marginal zone B-cell lymphoma and nodal marginal zone B-cell lymphoma according to clinical and therapeutic implications of the tumor. MALT lymphoma is the most common type of marginal zone lymphoma, and about 5-8% of all B-cell lymphomas are diagnosed as MALT lymphoma. MALT lymphomas are usually found in the gastrointestinal tract, mostly in the stomach associated with H pylori infection; the non-gastric MALT lymphoma can also be found in the salivary gland, lung, head and neck, ocular adnexa, skin, thyroid, or breast. However, the involvement of nasal cavity and nasopharynx is rare. Based on our recent experience and a review of related literature, we report a case of MALT lymphoma that occurred in the nasopharynx and thyroid gland, which were treated with localized radiotherapy.

Keyword

Mucosa-associated lymphoid tissue lymphoma; Nasopharynx; Thyroid gland

MeSH Terms

B-Lymphocytes
Breast
Gastrointestinal Tract
Head
Lung
Lymphoid Tissue
Lymphoma
Lymphoma, B-Cell
Lymphoma, B-Cell, Marginal Zone*
Lymphoma, Non-Hodgkin
Mucous Membrane
Nasal Cavity
Nasopharynx*
Neck
Radiotherapy
Salivary Glands
Skin
Stomach
Thyroid Gland*