Obstet Gynecol Sci.  2017 Sep;60(5):485-489. 10.5468/ogs.2017.60.5.485.

Estrogen-induced acute pancreatitis: A case report and literature review

Affiliations
  • 1Department of Obstetrics and Gynecology, Dongguk University Ilsan Hospital, Goyang, Korea. hsparkmd@gmail.com
  • 2Division of Gastroenterology & Hepatology, Department of Internal Medicine, Dongguk University Ilsan Hospital, Goyang, Korea.

Abstract

Estrogens are commonly used in gynecologic area, such as oral contraception, hormone replacement therapy, and in vitro fertilization-embryo transfer. Although estrogen is a common cause of acute drug-induced pancreatitis, there has been paucity of report in Korea. Clinical course of estrogen-induced acute pancreatitis is usually mild to moderate, but fetal case can occur. In addition, there can be a latency from the first administration to the symptom. Therefore, physicians should consider the possibility of the disease when a woman taking estrogen or previous history of taking estrogen presents with acute abdominal pain. Here, we report a case of estrogen-induced acute pancreatitis that occurred during the preparation for embryo transfer.

Keyword

Acute pancreatitis; Drug-induced acute pancreatitis; Estrogen

MeSH Terms

Abdominal Pain
Contraception
Embryo Transfer
Estrogens
Female
Hormone Replacement Therapy
Humans
In Vitro Techniques
Korea
Pancreatitis*
Estrogens

Figure

  • Fig. 1 (A) Mild swelling of pancreas head (arrow) with peripancreatic infiltration, the presence of peripancreatic fluid (arrow head) and fluid in the upper mesentery (admission day). (B) Increased of peripancreatic fluid collection (arrow head) (4th hospital day). (C) Decreased peripancreatic fluid collection (2 months after discharge).


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