Korean J Obstet Gynecol.  2012 Oct;55(10):707-712.

Factors affecting reproductive outcome of hysteroscopic adhesiolysis for intrauterine adhesion: Live-birth rate after surgery

Affiliations
  • 1Department of Obstetrics and Gynecology, Eulji University School of Medicine, Seoul, Korea. pwi3110@eulji.ac.kr

Abstract


OBJECTIVE
The purpose of this study is to assess the impact of various factors of hysteroscopic lysis of intrauterine adhesion on live-birth rate after surgery.
METHODS
Medical records of 54 patients suffering from infertility or recurrent spontaneous abortion were retrospectively analyzed. The independent variables were degree of intrauterine adhesion, surgical technique, use of intrauterine Foley catheter, insertion of intrauterine device, and dose of postoperative estradiol. Multivariate analysis as well as univariate analysis was performed.
RESULTS
Among the 54 patients, 17 patients gave live-birth. The degree of intrauterine adhesion was found to be a sole factor affecting the live-birth rate by univariate and multivariate analysis. The mechanical dissection with scissors had been resulted a higher live-birth rate against resectoscopic electrosurgery, but the difference was not statistically significant.
CONCLUSION
The degree of intrauterine adhesion is the most important factor affecting the live-birth. The uses of intrauterine Foley catheter, insertion of intrauterine device and dose of postoperative estradiol have little impact.

Keyword

Asherman's syndrome; Adhesiolysis; Hysteroscopy; Reproductive outcome

MeSH Terms

Abortion, Spontaneous
Catheters
Electrosurgery
Estradiol
Female
Gynatresia
Humans
Hysteroscopy
Infertility
Intrauterine Devices
Medical Records
Multivariate Analysis
Pregnancy
Retrospective Studies
Stress, Psychological
Tissue Adhesions
Estradiol

Figure

  • Fig. 1 Flowchart of patient selection.


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