J Korean Acad Oral Health.  2017 Sep;41(3):181-187. 10.11149/jkaoh.2017.41.3.181.

Comparative effects of aqueous single-phase and oil-water two-phase mouthrinses containing bamboo salt, magnolia bark and Centella asiatica extracts on reducing gingivitis: a randomized clinical trial

• Choi S
• Paik DI
• Jin BH

• KMID: 2392436
• DOI: http://doi.org/10.11149/jkaoh.2017.41.3.181

Abstract

OBJECTIVES
The aim of this study was to assess the antiplaque and antigingivitis effectiveness of aqueous single-phase and oil-water two-phase mouthrinses, containing bamboo salt, magnolia bark, and Centella asiatica extracts, in Korean adults.
METHODS
In this double-blinded clinical trial, a total of thirty-four participants aged over 19 years were randomly allocated to three experimental groups: 1) control group; 2) aqueous single-phase mouthrinse (ASM) group, and; 3) oil-water two-phase mouthrinse (OTM) group. The experimental mouthrinses all contained sodium fluoride, and the ASM and OTM contained additional ingredients of bamboo salt, magnolia bark, and Centella asiatica extracts. For the OTM, 50% essential oil was added to create an oil-water two-phase mouthrinse. A two-week randomized crossover design with a two-week washout period was applied. Following a complete dental prophylaxis, participants were instructed to use the prescribed mouthrinse twice daily for two weeks as an adjunct to their usual mechanical oral hygiene procedures. Pre- and post-experiment clinical examinations were performed to measure the plaque index (PI) and bleeding on probing (BOP) for the full mouth. Paired t-test was applied to compare the intergroup differences for all clinical variables.
RESULTS
Compared to the control group, ASM showed a significantly reduced BOP (P<0.05). However, there was no statistically significant difference in the effects of the three mouthrinses on reducing the PI.
CONCLUSIONS
The results of this study indicate that the use of an aqueous, single-phase mouthrinse containing bamboo salt, magnolia bark and Centella asiatica extracts could help alleviate gingivitis.

Keyword

Bamboo salt; Centella asiatica; gingivitis; magnolia bark; mouthrinse

MeSH Terms

Adult
Centella*
Cross-Over Studies
Dental Prophylaxis
Gingivitis*
Hemorrhage
Humans
Magnolia*
Mouth
Oral Hygiene
Sodium Fluoride
Sodium Fluoride

Figure

• 

  Fig. 1 The experiment scheme of the two-week randomized controlled trial with crossover design. Baseline and post-experiment clinical examinations were performed on the first and the last days of the trial. Trial A: daily use of the control mouthrinse for two-weeks; Trial B: daily use of the ASM for two-weeks; Trial C: daily use of the OTM for twoweeks.

• 

  Fig. 2 Changes in the mean bleeding on probing index after two-week experimental period. Bold denotes statistical significance at P<0.05 level.

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