Korean J Med.  2017 Aug;92(4):366-371. 10.3904/kjm.2017.92.4.366.

Understanding the Rome IV: Irritable Bowel Syndrome and Functional Diarrhea

  • 1Department of Internal Medicine, Gyeongsang National University College of Medicine, Jinju, Korea. imdrkim@naver.com


Irritable bowel syndrome (IBS) is a common, chronic functional gastrointestinal disorder affecting the large intestine, and presents as abdominal pain and/or discomfort, bloating, gas retention, diarrhea, and constipation. IBS impairs quality-of-life and requires long-term management. In 2016, the Rome Foundation introduced new IBS diagnostic criteria (the Rome IV criteria), and also revised the diagnostic algorithms for, and the multidimensional clinical profile (MDCP) of, functional gastrointestinal disorders. The IBS MDCP includes clinical data, the extent to which normal daily activities are affected, and psychosocial and physiological measures. The criteria seek to aid physicians in choosing appropriate treatment for IBS patients. Herein, we seek to provide evidence- based practical information on IBS and functional diarrhea. We review the new Rome diagnostic IV criteria, the MDCP, and the various IBS treatment options. We suggest that, in clinical practice, combination therapies may be useful to treat patients with IBS of various grades.


Irritable bowel syndrome; Functional diarrhea; Rome IV; Multidimensional clinical profile

MeSH Terms

Abdominal Pain
Gastrointestinal Diseases
Intestine, Large
Irritable Bowel Syndrome*
Full Text Links
  • KJM
export Copy
  • Twitter
  • Facebook
Similar articles
    DB Error: unknown error