Korean J Crit Care Med.  2017 Aug;32(3):265-274. 10.4266/kjccm.2017.00178.

The Association of Preoperative Body Mass Index with Acute Kidney Injury in Liver Transplantation Recipients: A Retrospective Study

• Park JY
• Park JH
• Lee SS
• Ri HS
• Kim HJ
• Choi YM
• Choi YJ
• Yoon JU

• KMID: 2391186
• DOI: http://doi.org/10.4266/kjccm.2017.00178

Abstract

BACKGROUND
Liver transplantation (LT) is a complicated procedure with a high incidence of postoperative acute kidney injury (AKI). Previous studies indicate that even transient or mild post-LT AKI can result in critical conditions, including prolonged stays in hospitals and intensive care units and increased morbidity and mortality. The aim of this study was to investigate the association between body mass index (BMI) and occurrence of AKI in LT recipients.
METHODS
Medical data from 203 patients who received LT surgery from January 2010 to August 2016 in a single university hospital setting were retrospectively collected and analyzed. Patients were classified as either underweight (BMI <20 kg/m²) or normal weight (20 ≤ BMI < 30 kg/m²). Demographic data, anesthetic methods, complications, and perioperative laboratory test values of each patient were assessed. Propensity analyses and logistic regression were performed to evaluate the association between BMI and post-LT AKI.
RESULTS
There was no significant difference in occurrence of post-LT AKI between underweight and normal weight patients. The underweight patient group had significantly longer hospital stay compared with the normal weight patient group (P = 0.023).
CONCLUSIONS
BMI classification was neither a positive nor negative predictor of postoperative AKI occurrence. However, patients with lower BMI had significantly longer hospital stay compared with their counterparts. Although our study was limited by its retrospective design, our observations suggest that lower BMI might play a role in post-LT AKI.

Keyword

acute kidney injury; body mass index; liver transplantation

MeSH Terms

Acute Kidney Injury*
Body Mass Index*
Classification
Humans
Incidence
Intensive Care Units
Length of Stay
Liver Transplantation*
Liver*
Logistic Models
Mortality
Retrospective Studies*
Thinness

Figure

• 

  Figure 1. A flow diagram of the progress through the study. ESRD: end-stage renal disease; HD: hemodialysis; BMI: body mass index.

Reference

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