Chonnam Med J.  2017 Sep;53(3):236-237. 10.4068/cmj.2017.53.3.236.

Benign Recurrent Pleomorphic Adenoma of the Parotid Gland with Perineural Space Invasion

• Roncati L
• Maiorana A

• KMID: 2390442
• DOI: http://doi.org/10.4068/cmj.2017.53.3.236

Abstract

No abstract available.

MeSH Terms

Adenoma, Pleomorphic*
Parotid Gland*

Figure

• 

  FIG. 1 Recurrent pleomorphic adenoma of the parotid gland: the tumor recurs inside the salivary tissue (A, yellow asterisks), it shows a typical myxoid appearance and a plurinodular growth pattern on panoramic histological view, and it involves the surgical margin (A, red arrows), highlighted by ink marking. Some neoplastic nests (A, yellow circle) spread along the perineural spaces (A, hematoxylin & eosin, 1.25×). At higher magnification, this phenomenon (B, yellow circle) is best appreciated (B, hematoxylin & eosin, 10×). Both neoplastic nests and nerves (C, black arrows) are brown-stained by immunohistochemistry for S100 protein (C, polyclonal, 10×); however, nerves (D, black arrows) are not reactive for pancytokeratins, which reveal in brown only the neoplastic nests (D, clone MNF116, 20×).

Reference

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