Korean J Ophthalmol.  2017 Oct;31(5):439-445. 10.3341/kjo.2016.0090.

Short-term Analysis of the Residual Volume of an Eye Drop Following 23-Gauge Microincision Vitrectomy Surgery

• Kang YK
• Im JC
• Shin JP
• Kim IT
• Park DH

• KMID: 2390287
• DOI: http://doi.org/10.3341/kjo.2016.0090

Abstract

PURPOSE
To evaluate the change of residual volume of eye drop after instillation in patients with 23-gauge microincision vitrectomy surgery (MIVS).
METHODS
Patient who were treated 23-gauge MIVS from November 2014 to July 2015 were included. The residual volume was defined as the amount of remnant eye drop in patient's eyes after instillation, calculated as the difference between instillation volume and spilled volume of eye drop. Calculation of residual volume of eye drop was performed one day before surgery, and daily from postoperative day 1 to day 5.
RESULTS
Forty consecutive patients were included. The residual volume of eye drop decreased from 30.3 ± 1.4 µL at baseline to 13.0 ± 1.5 µL at day 1, 18.3 ± 1.6 µL at day 2, 24.7 ± 1.5 µL at day 3, and 27.9 ± 1.4 µL in day 4, postoperatively (p < 0.001, respectively). The volume at postoperative day 5 was 29.4 ± 1.3 µL, but it was not different from the volume at baseline (p = 0.105). The change of residual volume was significantly correlated with postoperative chemosis (r = 0.672, p < 0.001) and effected by the number of quadrant with postoperative chemosis (p < 0.05).
CONCLUSIONS
This study shows that postoperative residual volume of eye drop after instillation decreased until postoperative day 4, and postoperative chemosis affects the change of residual volume. Thus, checking proper use of eye drops and teaching about instillation technique by physician is necessary for patients with 23-gauge MIVS.

Keyword

Eye drop; Chemosis; Residual volume; Vitrectomy

MeSH Terms

Humans
Ophthalmic Solutions
Residual Volume*
Vitrectomy*
Ophthalmic Solutions

Figure

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  Fig. 1 (A) The conjunctiva was divided into four parts (quadrants) that correspond to 3, 6, 9 or 12 clock hours. Conjunctival chemosis was judged to be present when the conjunctiva is higher than a third of the total height of the palpebral aperture. (B) An example case of presence of postoperative chemosis in all quadrants of the conjunctiva. SN = superonasal; ST = superotemporal; IN = inferonasal; IT = inferotemporal.

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  Fig. 2 The residual volume of eye drop changes following 23-gauge microincision vitrectomy surgery according to the postoperative follow-up period. Repeated-measures analysis of variance showed significant decrease in residual volume from the baseline at postoperative day 1, 2, 3 and 4 (p < 0.001, respectively). *p < 0.05 by repeated-measures analysis of variance with Bonferroni correction.

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