J Rheum Dis.
2017 Aug;24(4):241-245. 10.4078/jrd.2017.24.4.241.
A Case of Polymyositis Associated with Immunoglobulin A Nephropathy
- Affiliations
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- 1Division of Rheumatology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
- 2Department of Pathology, Yonsei University College of Medicine, Seoul, Korea.
- 3Division of Nephrology, Department of Internal Medicine, National Health Insurance Service Ilsan Hospital, Goyang, Korea.
- 4Department of Pathology, National Health Insurance Service Ilsan Hospital, Goyang, Korea.
- 5Division of Rheumatology, Department of Internal Medicine, National Health Insurance Service Ilsan Hospital, Goyang, Korea. jinsulog@naver.com
- KMID: 2389066
- DOI: http://doi.org/10.4078/jrd.2017.24.4.241
Abstract
- Polymyositis (PM) is a chronic inflammatory disease that predominantly affects muscles. Systemic organ involvement, including the respiratory and gastrointestinal tracts, is frequently observed in PM, but renal involvement is rare. Herein, we report the case of a 56-year-old woman presenting with weight gain, edema, and generalized myalgia. Laboratory tests revealed elevated creatinine kinase level, hypoalbuminemia, and proteinuria. Histopathological examination of muscle biopsy revealed inflammatory myositis, and a renal biopsy confirmed immunoglobulin A (IgA) nephropathy. Based on the clinico-pathological results, the patient was diagnosed with PM with IgA nephropathy. This is a report of a rare occurrence of IgA nephropathy in a patient with PM presenting with chronic glomerulonephritis.
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