Ann Dermatol.
2017 Aug;29(4):487-490. 10.5021/ad.2017.29.4.487.
Lobulated Bowen's Disease with a Clear Cell Change
- Affiliations
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- 1Department of Dermatology, School of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, Korea. tyyoon@chungbuk.ac.kr
- KMID: 2388950
- DOI: http://doi.org/10.5021/ad.2017.29.4.487
Abstract
- Bowen's disease usually manifests as a slowly enlarging erythematous scaly patch or plaque. An uncommon variant of Bowen's disease showing a verrucous appearance has been reported and a distinct variant with a prominent clear cell change on histopathology, in addition to a verrucous surface change, was also reported. We describe novel form of Bowen's disease having a cerebriform appearance and showing histopathologically a significant clear cell change and propose that the clinical term "lobulated Bowen's disease" would be compatible for the description of this unique clinical variant. From a histopathological point of view, the precise definition and etiopathogenesis of the clear cell change in Bowen's disease should be elucidated.
