Ann Dermatol.  2017 Aug;29(4):483-486. 10.5021/ad.2017.29.4.483.

Cutaneous Plasmacytoma: Metastasis of Multiple Myeloma at the Fracture Site

• Yoo J
• Jo M
• Kim MS
• Jue MS
• Park HJ
• Choi KH

• KMID: 2388949
• DOI: http://doi.org/10.5021/ad.2017.29.4.483

Abstract

Multiple myeloma (MM) can be defined as a malignancy with monoclonal plasma cell proliferation. A 66-year-old man presented with pruritic erythematous to purplish plaque grouped nodule with black pigmentations and purpura on the right forearm. The patient was diagnosed with MM about five years prior to the visit at our hospital. Erythematous plaque on his right arm grew rapidly in size over one month and appeared about seven months after the fracture surgery. Skin biopsy showed multiple plasma cell infiltration with monoclonality for lambda light chain, which was consistent with cutaneous plasmacytoma. The patient refused to be treated and died two months later. We herein report an interesting case of cutaneous plasmacytoma at the surgical site of fracture repair.

Keyword

Cutaneous plasmacytoma; Fracture site; Multiple myeloma; Surgical site

MeSH Terms

Aged
Arm
Biopsy
Forearm
Humans
Multiple Myeloma*
Neoplasm Metastasis*
Pigmentation
Plasma Cells
Plasmacytoma*
Purpura
Skin

Figure

• 

  Fig. 1 Erythematous to purplish plaque with black pigmentations and purpura on the right forearm.

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  Fig. 2 (A) Skin biopsy showing multiple plasma infiltration (H&E, ×200). (B) Atypical cells showing pleomorphism with hyperchromatic and enlarged nuclei (H&E, ×400). (C) Monoclonality for lambda light chain (lambda light chain, ×200). (D) Cells were stained positive for CD138 (CD138, ×200).

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