J Korean Neurol Assoc.
2017 Aug;35(3):151-154. 10.17340/jkna.2017.35.3.7.
Reversible Cerebral Vasoconstriction Syndrome Presenting with Bilateral Occipital Hemorrhage after the Subcutaneous Injection of Synthetic Gonadotropin Releasing Hormone
- Affiliations
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- 1Department of Neurology, Seoul National University College of Medicine, Seoul, Korea. mkhan@snu.ac.kr
- 2Department of Neurology, Seoul National University Bundang Hospital, Seongnam, Korea.
- 3Department of Radiology, Seoul National University Bundang Hospital, Seongnam, Korea.
- KMID: 2388634
- DOI: http://doi.org/10.17340/jkna.2017.35.3.7
Abstract
- Reversible cerebral vasoconstriction syndrome (RCVS) is a heterogeneous group of cerebrovascular disease. The pathophysiology of RCVS is unknown, but a disturbance in cerebral vascular tone is one of hypothesis. Long-term use of Gonadotropin-releasing hormone (GnRH) agonists can induce a pseudomenopausal state in which estrogen production are suppressed. It might lead to reduced arterial relaxation by estrogen withdrawal. We report a case of RCVS after the injection of synthetic analogue of GnRH.
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