J Korean Neurol Assoc.  2017 Aug;35(3):148-150. 10.17340/jkna.2017.35.3.6.

Myasthenia Gravis with Thymoma Recurrence 20 Years after Thymectomy: What Is the Optimal Follow-up Duration?

Affiliations
  • 1Department of Neurology, Catholic University of Daegu, School of Medicine, Daegu, Korea. jihelpgod@cu.ac.kr
  • 2Department of Neurology, CHA Gumi Medical Center, CHA University, Daegu, Korea.
  • 3Department of Thoracic and Cardiovascular Surgery, Catholic University of Daegu, School of Medicine, Daegu, Korea.

Abstract

Thymoma occurs in about 20% of patients with myasthenia gravis (MG), but the recurrence of thymoma has rarely been reported. A 68-year-old man presented with ptosis and weakness of the neck muscles. He had undergone thymectomy for ocular MG with invasive thymoma 20 years previously. Chest computed tomography revealed recurrence of the thymoma. This 20-year period is, to our knowledge, the longest reported interval for recurrence of an MG-associated thymoma. The literature on the optimal follow-up duration after thymectomy is reviewed.

Keyword

Myasthenia gravis; Thymoma; Recurrence

MeSH Terms

Aged
Follow-Up Studies*
Humans
Myasthenia Gravis*
Neck Muscles
Recurrence*
Thorax
Thymectomy*
Thymoma*
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