Obstet Gynecol Sci.  2017 Jul;60(4):401-404. 10.5468/ogs.2017.60.4.401.

Fibroepithelial polyp of the vulva accompanied by lymphangioma circumscriptum

• Lee MH
• Hwang JY
• Lee JH
• Kim DH
• Song SH

• KMID: 2386286
• DOI: http://doi.org/10.5468/ogs.2017.60.4.401

Abstract

Fibroepithelial polyp (FEP) and lymphangioma circumscriptum (LC) of the vulva are rare diseases that occur generally in young to middle-aged women. The pathogenesis of FEP is not clearly understood. Several previous cases have suggested that a hormonal influence may be a predisposing condition for developing FEP with or without chronic inflammation. A 68-year-old postmenopausal woman presented with a history of multiple raised lesions on the vulva with a 1-year duration. Additionally, a pedunculated mass had appeared 6 months earlier in the left lower labia minora. The patient underwent simple excision by electrocautery. The final pathological diagnosis was FEP with LC. In this case, the development of FEP was associated only with chronic inflammation induced by LC. Therefore, the case supports the hypothesis that a chronic inflammatory process may be related to the development of FEP even without hormonal influence.

Keyword

Lymphangioma; Neoplasms, fibroepithelial; Postmenopause; Vulva

MeSH Terms

Aged
Diagnosis
Electrocoagulation
Female
Humans
Inflammation
Lymphangioma*
Neoplasms, Fibroepithelial
Polyps*
Polytetrafluoroethylene
Postmenopause
Rare Diseases
Vulva*
Polytetrafluoroethylene

Figure

• 

  Fig. 1 Clinical appearance of the vulva. (A) Preoperation. Multiple frog spawn-like lesions and a large (5 cm×3.5 cm) pedunculated polyp were present. (B) Postoperation. The lesions were no longer present. M, fibroepithelial polyp.

• 

  Fig. 2 Pathologic findings of lesions. (A) The large nodule revealed diffuse fibrous stroma and hyperplastic epidermis where few lymphatic vessels were dilated (trichrome stain, ×40). (B) The dilated lymphatic vessels were lined by endothelial cells positive for D2-40. Adjacent small blood vessels were unstained by D2-40 (immunostain for D2-40, ×200).

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