Ann Rehabil Med.  2012 Dec;36(6):770-775.

Factors Affecting Bone Mineral Density in Adults with Cerebral Palsy

Affiliations
  • 1Department and Research Institute of Rehabilitation Medicine, Yonsei University College of Medicine, Seoul 120-752, Korea. srcho918@yuhs.ac

Abstract


OBJECTIVE
To clarify factors affecting bone mineral density (BMD) in adults with cerebral palsy (CP). METHOD: Thirty-five patients with CP participated in this study. Demographic data including gender, age, body mass index (BMI), subtype according to neuromotor type and topographical distribution, ambulatory function, and functional independence measure (FIM) were investigated. The BMD of the lumbar spine and femur were measured using Dual-energy X-ray absorptiometry, and the factors affecting BMD were analyzed.
RESULTS
The BMD had no significant association with factors such as gender, age, and subtype in adults with CP. However, BMI was significantly correlated with the BMD of lumbar spine and femur (p<0.05). The FIM score was also positively correlated with the BMD of femur (p<0.05). Moreover, CP patients with higher ambulatory function had significantly higher BMD of femur (p<0.05).
CONCLUSION
These findings suggest that BMI and functional levels such as FIM and ambulatory function can affect BMD in adults with CP. The results might be used as basic data, suggesting the importance of treatment including weight bearing exercise and gait training in adults with CP.

Keyword

Bone mineral density; Adult; Cerebral palsy; Body mass index; Functional level

MeSH Terms

Absorptiometry, Photon
Adult
Body Mass Index
Bone Density
Cerebral Palsy
Femur
Gait
Humans
Spine
Weight-Bearing

Figure

  • Fig. 1 Correlation between BMI and BMD in adults with cerebral palsy. (A) Spine L2-4, (B) Femur total. BMD: Bone mineral density, BMI: Body mass index.

  • Fig. 2 Correlation between BMD and FIM score in adults with cerebral palsy. (A) Spine L2-4, (B) Femur total. BMD: Bone mineral density, FIM: Functional independence measure.


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