Korean J Gastroenterol.  2017 Feb;69(2):129-134. 10.4166/kjg.2017.69.2.129.

Clinical Features of Spontaneous Bacterial Peritonitis: A 10-year Experience from a Single Center

• Na HY
• Kim JH
• Choe WH
• Kwon SY
• Yoo BC

• KMID: 2383422
• DOI: http://doi.org/10.4166/kjg.2017.69.2.129

Abstract

BACKGROUND/AIMS
Spontaneous bacterial peritonitis (SBP) is one of critical complications in liver cirrhosis patients with ascites. We aimed to review clinical course of SBP patients in a 10-year period from single center.
METHODS
This study enrolled SBP patients between 2005 and 2015. Their medical records were reviewed. The laboratory findings of serum and ascites were examined, and characteristics of isolated microorganisms in ascites were analyzed.
RESULTS
Total 51 patients were enrolled. Male patients were predominant (64.7%), and mean age was 59.20 years. The most common etiology of cirrhosis was alcohol (41.2%), followed by hepatitis B (39.2%). Microorganism was isolated from the ascites in 31 patients (60.78%). The proportions of Gram negative and Gram positive were 80.64% and 19.36%. The proportions of Escherichia coli, Klebsiella, and Streptococcus species were 29.41%, 19.61% and 11.76%. Among Escherichia colis, 4 cases were ESBL positive (7.84%). The most commonly used first-line antibiotic was cefotaxime (80.40%). Prophylactic antibiotics treatment was performed only in 8 patients, and SBP was recurred in 7 patients (13.72%). When comparing the SBP recurrence group and the non-recurrence group, there were no significant differences in laboratory findings of serum and ascitic fluid.
CONCLUSIONS
SBP is still a critical complication in cirrhosis patients with ascites, and the clinical features of SBP have not been altered much compared with those in 1990's. The effective treatment of SBP is still very important for a better prognosis of cirrhosis patients.

Keyword

Liver cirrhosis; Peritonitis; Microorganism; Bacteria

MeSH Terms

Anti-Bacterial Agents
Ascites
Ascitic Fluid
Bacteria
Cefotaxime
Escherichia coli
Fibrosis
Hepatitis B
Humans
Klebsiella
Liver Cirrhosis
Male
Medical Records
Peritonitis*
Prognosis
Recurrence
Streptococcus
Anti-Bacterial Agents
Cefotaxime

Figure

• 

  Fig. 1. Study flowchart, 2005–2015. KUH, Konkuk University Hospital.

Reference

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