Lab Med Online.  2017 Jul;7(3):157-160. 10.3343/lmo.2017.7.3.157.

A Case of Streptococcus gallolyticus subsp. gallolyticus Bacteremia in Liver Cirrhosis

  • 1Department of Laboratory Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea.


Streptococcus bovis bacteremia in humans has been traditionally associated with infective endocarditis, colorectal cancer, and liver cirrhosis. S. bovis strains were previously categorized by biotype, but since the 2000s, they have been reclassified by DNA homology. We report a case of S. gallolyticus subsp. gallolyticus bacteremia, identified by 16S rRNA sequencing, in a patient diagnosed with liver cirrhosis. A 61-yr-old man with a history of liver cirrhosis presented to the hospital with a complaint of fever. Blood culture revealed the presence of gram-positive cocci, and the isolated organism was identified as S. bovis by the MicroScan identification kit (Beckman Coulter, USA), but as Enterococcus saccharolyticus by the Vitek 2 identification kit (bioMérieux, USA). The organism was finally confirmed as S. gallolyticus subsp. gallolyticus by 16S rRNA sequencing.


Bacteremia; Liver cirrhosis; Streptococcus gallolyticus; 16S rRNA sequencing
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