J Pathol Transl Med.  2015 May;49(3):230-235. 10.4132/jptm.2015.03.21.

Effectiveness and Limitations of Core Needle Biopsy in the Diagnosis of Thyroid Nodules: Review of Current Literature

Affiliations
  • 1Department of Radiology, Severance Hospital, Research Institute of Radiological Science, Yonsei University College of Medicine, Seoul, Korea. ekkim@yuhs.ac

Abstract

Fine needle aspiration (FNA) is currently accepted as an easy, safe, and reliable tool for the diagnosis of thyroid nodules. Nonetheless, a proportion of FNA samples are categorized into non-diagnostic or indeterminate cytology, which frustrates both the clinician and patient. To overcome this limitation of FNA, core needle biopsy (CNB) of the thyroid has been proposed as an additional diagnostic method for more accurate and decisive diagnosis for thyroid nodules of concern. In this review, we focus on the effectiveness and limitations of CNB, and what factors should be considered when CNB is utilized in the diagnosis of thyroid nodules.

Keyword

Thyroid; Neoplasm; Core needle biopsy; Ultrasonography

MeSH Terms

Biopsy, Fine-Needle
Biopsy, Large-Core Needle*
Diagnosis*
Humans
Thyroid Gland
Thyroid Nodule*
Ultrasonography

Cited by  4 articles

Evaluation of Modified Core-Needle Biopsy in the Diagnosis of Thyroid Nodules
Soomin Ahn, Sejin Jung, Ji-Ye Kim, Jung Hee Shin, Soo Yeon Hahn, Young Lyun Oh
Korean J Radiol. 2018;19(4):656-664.    doi: 10.3348/kjr.2018.19.4.656.

Degenerating Thyroid Nodules: Ultrasound Diagnosis, Clinical Significance, and Management
Jie Ren, Jung Hwan Baek, Sae Rom Chung, Young Jun Choi, Chan Kwon Jung, Jeong Hyun Lee
Korean J Radiol. 2019;20(6):947-955.    doi: 10.3348/kjr.2018.0599.

Core-Needle Biopsy Does Not Show Superior Diagnostic Performance to Fine-Needle Aspiration for Diagnosing Thyroid Nodules
Ilah Shin, Eun-Kyung Kim, Hee Jung Moon, Jung Hyun Yoon, Vivian Youngjean Park, Si Eun Lee, Hye Sun Lee, Jin Young Kwak
Yonsei Med J. 2020;61(2):161-168.    doi: 10.3349/ymj.2020.61.2.161.

Core Needle Biopsy Is a More Conclusive Follow-up Method Than Repeat Fine Needle Aspiration for Thyroid Nodules with Initially Inconclusive Results: A Systematic Review and Meta-Analysis
Jung-Soo Pyo, Jin Hee Sohn, Guhyun Kang
J Pathol Transl Med. 2016;50(3):217-224.    doi: 10.4132/jptm.2016.02.15.


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