Int J Thyroidol.  2017 May;10(1):1-4. 10.11106/ijt.2017.10.1.1.

Epidemiologic Association between Obesity and Thyroid Nodules

• Ahn HY

• KMID: 2379355
• DOI: http://doi.org/10.11106/ijt.2017.10.1.1

Abstract

Recently, the incidence of thyroid nodule has been rising due to the usage of ultrasonography in health check-up. Also, modern society is faced with increasing rates of obesity by sedentary life style and high caloric intake. Obesity is closely related to metabolic syndrome and insulin resistance. Insulin resistance leads to hyperinsulinemia, increased insulin-like growth factor 1 and alteration of adipocytokine level. These factors not only have a role in metabolic regulation, but they also have mitogenic effect in cell proliferation. Epidemiologic and clinical evidence about the association between obesity and thyroid nodule are reviewed in this section.

Keyword

Thyroid nodules; Obesity; Insulin resistance; Metabolic syndrome X

MeSH Terms

Cell Proliferation
Energy Intake
Hyperinsulinism
Incidence
Insulin Resistance
Life Style
Metabolic Syndrome X
Obesity*
Thyroid Gland*
Thyroid Nodule*
Ultrasonography