J Korean Ophthalmol Soc.  2017 Apr;58(4):408-414. 10.3341/jkos.2017.58.4.408.

Long-term Changes of Endothelial Cell Density after Pars Plana Vitrectomy with Fragmentation

• Choi SY
• Han JY
• Eom Y
• Kim SW

• KMID: 2376595
• DOI: http://doi.org/10.3341/jkos.2017.58.4.408

Abstract

PURPOSE
To evaluate the long-term changes in cornea endothelial cell density (ECD) after pars plana vitrectomy (PPV) with fragmentation.
METHODS
Twenty patients (20 eyes) who underwent PPV with fragmentation and who were followed up for 2 years were enrolled in this retrospective study. The cornea ECD, coefficient of variation (CV), and hexagonality (HA) were calculated using a specular microscopy at 1, 3, 6, 12 months, and 2 years after surgery.
RESULTS
The preoperative mean ECD was 1,782 ± 623 cells/mm², and the postoperative mean ECD did not significantly change at 1, 3, 6, and 12 months. Additionally, there were no significant changes in CV or HA. At 2 years after surgery, the mean ECD was 1,722 ± 532 cells/mm², the mean CV was 35.50 ± 3.03%, and the mean HA was 53.00 ± 4.91%. There were no significant changes in ECD, CV, or HA preoperatively and postoperatively at 1, 3, 6, and 12 months.
CONCLUSIONS
In this study, the mean ECD did not significantly decrease after PPV with fragmentation at 2 years after surgery. A PPV with fragmentation was an appropriate surgical procedure for patients with low cornea endothelial cell density.

Keyword

Cornea endothelial cell density; Pars plana vitrectomy with fragmentation

MeSH Terms

Cornea
Endothelial Cells*
Humans
Microscopy
Retrospective Studies
Vitrectomy*

Figure

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  Figure 1. Changes in endothelial cell density(ECD). No sig-nificant changes in ECD at 1, 3, 6, 12 and 24 months after pars plana vitrectomy with fragmentation.

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  Figure 2. Changes in coefficient of variation (CV) of endothe-lial cells. No significant changes in CV at 1, 3, 6, 12 and 24 months after pars plana vitrectomy with fragmentation.

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  Figure 3. Changes in endothelial cell hexagonality (HA). No significant changes in HA at 1, 3, 6, 12 and 24 months after pars plana vitrectomy with fragmentation.

Reference

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