Korean J Endocr Surg.  2008 Jun;8(2):118-122. 10.16956/kjes.2008.8.2.118.

Analysis of Factors Affecting Local Recurrences after Thyroid Surgery in Low Risk Papillary Thyroid Carcinomas

• Lim SW
• Park SJ
• Cho H
• Gwak G
• Yang KH
• Bae BN
• Kim KW
• Kim HJ
• Kim YD
• Han S

• KMID: 2375864
• DOI: http://doi.org/10.16956/kjes.2008.8.2.118

Abstract

PURPOSE
This study analyzed factors affecting local recurrences in AGES low risk papillary thyroid carcinomas (PTCs).
METHODS
The clinical records of 89 patients who underwent thyroidectomy because of PTC were reviewed. Seventy patients had belonged to low risk PTC according to the AGES classification scheme. The clinical data of these patients concerning disease recurrence was analyzed considering age, gender, operative methods, tumor size, lymph node (LN) metastasis, postoperative radioactive iodine scan (RI scan ¹³¹I), and Synthyroid® intake.
RESULTS
Of the 70 patients, 56 were female (80%). Thirtyseven patients underwent total thyroidectomy with central neck LN dissection and 33 patients underwent partial thyroidectomy with ipsilateral central neck LN dissection. Mean tumor size was 2 cm (0.4~6 cm) and 31 patients had LN metastasis. Levels were <1µg/L in all patients who underwent total thyroidectomy but were 1~10µg/L in patients who received partial thyroidectomy thyroglobulin. Local recurrencein AGES low risk papillary carcinomas was significantly associated with tumor size >2 cm (P=0.030) and partial thyroidectomy (P=0.045). There was no significant association between local recurrence and age, gender, extrathyroidal extension, LN metastasis, RI scan ¹³¹I, or Synthyroid® intake.
CONCLUSION
Partial thyroidectomy and tumor size >2 cm are significantly associated with local recurrence in AGES low risk papillary thyroid carcinomas.

Keyword

AGES; Local recurrence; Papillary thyroid carcinoma; Thyroidectomy

MeSH Terms

Carcinoma, Papillary
Classification
Female
Humans
Iodine
Lymph Nodes
Neck
Neoplasm Metastasis
Recurrence*
Thyroglobulin
Thyroid Gland*
Thyroid Neoplasms*
Thyroidectomy
Iodine
Thyroglobulin