Ann Surg Treat Res.  2017 Apr;92(4):184-190. 10.4174/astr.2017.92.4.184.

Factors predicting outcomes of laparoscopic Nissen fundoplication for gastroesophageal reflux disease: experience at a single institution in Korea

• Park JM
• Kim BJ
• Kim JG
• Chi KC

• KMID: 2374683
• DOI: http://doi.org/10.4174/astr.2017.92.4.184

Abstract

PURPOSE
Laparoscopic fundoplication is considered the standard surgical treatment for gastroesophageal reflux disease (GERD) in Western countries. However, some patients experience poor surgical outcomes with this procedure. The study aimed to identify the predictive factors of the surgical outcomes of laparoscopic Nissen fundoplication for the treatment of Korean GERD patients.
METHODS
Sixty-one patients with GERD were treated using laparoscopic Nissen fundoplication between November 2012 and February 2015. Symptom control rates were compared according to clinical and surgical factors to identify predictive factors of successful surgical outcomes.
RESULTS
Thirty-five men and 26 women were enrolled. Preoperatively, typical symptoms were present in 60 patients (98%), while atypical symptoms were present in 40 patients (66%). Postoperatively, typical symptoms were controlled in 51 of 60 patients (85.0%), while atypical symptoms were controlled in 33 of 40 patients (82.5%). Overall, at 6 months postsurgery, 54 (88.5%) reported some resolution of GERD symptoms, with 48 (78.7%) achieving complete control. Patients who exhibited a good response to proton pump inhibitor therapy had a significantly greater rate of complete symptom control (P = 0.035).
CONCLUSION
Laparoscopic fundoplication is effective for controlling GERD symptoms. Response to preoperative proton pump inhibitor was a predictor of successful outcome.

Keyword

Gastroesophageal reflux disease; Fundoplication; Laparoscopy; Treatment outcomes

MeSH Terms

Female
Fundoplication*
Gastroesophageal Reflux*
Humans
Korea*
Laparoscopy
Male
Proton Pumps
Proton Pumps

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