Korean J Ophthalmol.  2016 Jun;30(3):234-235. 10.3341/kjo.2016.30.3.234.

Primary Systemic Amyloidosis Involving the Lacrimal Sac

• Kim J
• Kim L
• Kang SM

• KMID: 2373979
• DOI: http://doi.org/10.3341/kjo.2016.30.3.234

Abstract

No abstract available.

MeSH Terms

Aged, 80 and over
Amyloidosis/*complications/diagnosis
Biopsy
Dacryocystorhinostomy/methods
Humans
Lacrimal Apparatus/*diagnostic imaging/surgery
Lacrimal Apparatus Diseases/*diagnosis/etiology/surgery
Male
Tomography, X-Ray Computed

Figure

• 

  Fig. 1 (A) Preoperative computed tomography shows swelling of right medial canthal area and dilatation of both lacrimal sacs with increased peripheral enhancement. (B) Hematoxylin and eosin staining showed eosinophilic amorphous material deposition in stroma (×200). (C) Congo red staining revealed orange-colored amyloid deposits (×200). (D) Congo red positive with birefringence under a polarizing microscope (×200).

Reference

1. Aryasit O, Preechawai P, Kayasut K. Clinical presentation, treatment, and prognosis of periocular and orbital amyloidosis in a university-based referral center. Clin Ophthalmol. 2013; 7:801–805.

2. Kang YS, Choi W, Yoon KC. Primary systemic amyloidosis of the eyelid: a case report. J Korean Ophthalmol Soc. 2015; 56:1117–1121.

3. Leung N, Nasr SH, Sethi S. How I treat amyloidosis: the importance of accurate diagnosis and amyloid typing. Blood. 2012; 120:3206–3213.

4. Marcet MM, Roh JH, Mandeville JT, Woog JJ. Localized orbital amyloidosis involving the lacrimal sac and nasolacrimal duct. Ophthalmology. 2006; 113:153–156.

5. Leibovitch I, Selva D, Goldberg RA, et al. Periocular and orbital amyloidosis: clinical characteristics, management, and outcome. Ophthalmology. 2006; 113:1657–1664.