Korean J Gastroenterol.  2015 Jul;66(1):59-63. 10.4166/kjg.2015.66.1.59.

Inflammatory Hepatic Adenoma

• Lee JS
• Jeong EK
• Kim EK
• An C
• Kim HG
• Kim SU
• Han KH

• KMID: 2373314
• DOI: http://doi.org/10.4166/kjg.2015.66.1.59

Abstract

No abstract available.

MeSH Terms

Adenoma, Liver Cell/*diagnosis/diagnostic imaging/pathology
Aged
Antigens, CD34/metabolism
Bile Ducts, Intrahepatic/pathology
C-Reactive Protein/metabolism
Female
Humans
Liver Neoplasms/*diagnosis/diagnostic imaging/pathology
Magnetic Resonance Imaging
Serum Amyloid A Protein/metabolism
Tomography, X-Ray Computed
Antigens, CD34
C-Reactive Protein
Serum Amyloid A Protein

Figure

• 

  Fig. 1. Abdominopelvic CT. In the hepatovenous phase, a 3.2-cm sized hypovascular mass is seen in S5/6 of the liver.

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  Fig. 2. MRI findings. A 3.2-cm sized mass in S5 of the liver shows heterogeneously increased signal on T2-weighted image (A) and delayed enhancement on 15 minute delayed phase (B). Multiple small hypovascular noncystic lesions are also found in the liver (C).

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  Fig. 3. Pathologic findings of an initial biopsy specimen. (A) Sinusoidal dilatation and attenuated hepatic cords are seen (H&E stain, ×100).(B) Sinusoidal capillarization in the lesion is evident upon CD34 immunohistochemical staining (CD34 stain, ×40). (C) An inflammatory protein, CRP is positive (CRP stain, ×100). (D) -catenin shows an intact membranous expression (-catenin stain, ×100).

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  Fig. 4. Follow-up MRI. The hepatic mass in S5/6 of the liver has enlarged from 3.1 to 4.1 cm (A, B), and the number and sizes of small hypovascular lesions in both hepatic lobes have increased (C).

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  Fig. 5. Pathologic findings of a follow-up biopsy specimen. (A) Similar to that of the initial biopsy findings, sinusoidal dilatation and sinusoidal capillarization are noted (H&E stain, ×40). Sinusoidal capillarization (B; CD34 stain, ×40), CRP (C; CRP stain, ×100), amyloid (D; amyloid A stain,×200) are positive in the tumor cells.

Reference

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