J Rheum Dis.  2017 Feb;24(1):60-61. 10.4078/jrd.2017.24.1.60.

A Case of Paget's Disease Involving Pelvic Bone in a Patient with Tophaceous Gouty Arthritis

• Park EJ
• Kim SH
• Kim J

• KMID: 2371680
• DOI: http://doi.org/10.4078/jrd.2017.24.1.60

Abstract

No abstract available.

MeSH Terms

Arthritis, Gouty*
Humans
Pelvic Bones*

Figure

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  Figure 1. (A) Multiple distal interphalangeal joints destruction with tophi on plain radiography of hands, (B) active arthritis and osteomyelitis bilateral hands on delayed phase of 3-phase bone scan and (C) active bone lesion on pelvic bone, left femoral head and proximal femur on bone scan.

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  Figure 2. Sunburst lesion of left proximal femur on plain radiography of hips (arrow).

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  Figure 3. Bone marrow biopsy. (A) Irregularly thickened bony trabeculae with distinct cement lines (H&E stain, ×100), and (B) increased activity of multinucleated osteoclast (arrowhead) and osteoblast (arrow) (H&E stain, ×200).

Reference

1. Bolland MJ, Cundy T. Paget's disease of bone: clinical review and update. J Clin Pathol. 2013; 66:924–7.

2. Ralston SH, Langston AL, Reid IR. Pathogenesis and management of Paget's disease of bone. Lancet. 2008; 372:155–63.

3. Lluberas-Acosta G, Hansell JR, Schumacher HR Jr. Paget's disease of bone in patients with gout. Arch Intern Med. 1986; 146:2389–92.

4. Altman RD. Musculoskeletal manifestations of Paget's disease of bone. Arthritis Rheum. 1980; 23:1121–7.