J Korean Diet Assoc.  2017 Feb;23(1):39-53. 10.14373/JKDA.2017.23.1.39.

Association of Diabetes with Serum Vitamin D in Korean Adults : Analysis of the Korea National Health and Nutrition Examination Survey (2013~2014)

Affiliations
  • 1Division of Food and Nutrition, Chonnam National University, Gwangju 61186, Korea. sosung75@jnu.ac.kr

Abstract

Insufficient vitamin D intake is a major health problem around the world. Recently, many studies have suggested that vitamin D intake may influence insulin resistance. However, little is known about the association between vitamin D and diabetes mellitus. The aim of this study was to investigate the association between serum 25-hydroxy vitamin D (25(OH)D) levels and diabetes mellitus in Korean adults. This study was a cross-sectional analysis of 3,686 participants of the Korean National Health and Nutrition Examination Survey (KNHANES) 2013~2014 aged 19 years and higher. The results showed that the mean serum 25-hydroxy vitamin D (25(OH)D) level in Korean adults was 16.77 ng/mL, and 74.2% of them had an insufficient serum 25-hydroxy vitamin D (25(OH)D) level (below 20 ng/mL). In normal and pre-diabetic groups, the serum 25-hydroxy vitamin D (25(OH)D) level significantly increased with age (P<0.001), but there was no significant difference relative to age in the diabetic group. Low vitamin D levels (25-hydroxy vitamin D <10 ng/mL) were associated with increased fasting blood glucose levels, compared with optimal vitamin D levels (25-hydroxy vitamin D >30 ng/mL), after adjusting for variables that may affect fasting blood glucose, but this result was not significant. In conclusion, although no significant association was observed between diabetes prevalence and vitamin D levels in this study, further studies are needed because the effect of vitamin D on diabetes remains controversial. This nutrient plays a crucial role in the body, and levels are insufficient in the Korean population.

Keyword

diabetes mellitus; vitamin D deficiency; 25-hydroxy vitamin D; Korean National Health and Nutrition Examination Survey (KNHANES)

MeSH Terms

Adult*
Blood Glucose
Cross-Sectional Studies
Diabetes Mellitus
Fasting
Humans
Insulin Resistance
Korea*
Nutrition Surveys*
Prevalence
Vitamin D Deficiency
Vitamin D*
Vitamins*
Blood Glucose
Vitamin D
Vitamins
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