Korean J Psychosom Med.  2016 Dec;24(2):146-156. 10.0000/kjpm.2016.24.2.146.

Associations between Vasomotor Symptoms and Depression, Stress and Quality of Life in Midlife Women

Affiliations
  • 1Department of Psychiatry, Korea University College of Medicine, Seoul, Korea. shaeng@korea.ac.kr
  • 2Korea University Mental Health Research Institute, Seoul, Korea.
  • 3Health Promotion Research Institute, Korea Association of Health Promotion, Seoul, Korea.

Abstract


OBJECTIVES
The aim of this study was to evaluate the associations between vasomotor symptoms and factors such as sociodemographics, health behaviors, medical condition, depression, stress, anxiety, attitude toward menopause, and quality of life.
METHODS
We conducted a cross-sectional study in peri- and post-menopausal women enrolled by the Korean Association of Health Promotion. Subjects submitted self-report questionnaires about vasomotor symptoms and other clinical symptoms. Associations between vasomotor symptoms and clinical variables were analyzed using stepwise multiple regression analyses.
RESULTS
1951 women completed self-report questionnaires and 1022 women were enrolled in the study. The prevalence of vasomotor symptoms in peri- and post-menopausal women was 63.9%. Variables showing significant differences between subjects with vasomotor symptoms and subjects without them were score of Beck Depression Inventory, Brief Encounter Psychosocial Instrument-Korean Version, proportions of clinically significant depression(Beck Depression Inventory≥16), Menopausal rating scale, attitude towards menopause, the 4 subscales of World Health Organization Quality of Life-BREF(Physical health, psychological, social relationships, environment), and a History of Premenstrual syndrome/Premenstrual dysphoric disorder. Stepwise multiple regression analyses indicated that Beck Depression Inventory, Brief Encounter Psychosocial Instrument-Korean Version, Menopausal Rating Scale, and the Psychological subscale of World Health Organization Quality of Life -BREF show associations with vasomotor symptoms.
CONCLUSIONS
Menopausal vasomotor symptoms are associated with various psychological factors, especially with depression. Midlife women suffering vasomotor symptoms should therefore be screened for depression. Future prospective studies where clinical subjects are diagnosed using structured interviews, focusing on the causal relationship between depression and vasomotor symptoms are necessary.

Keyword

Midlife women; Vasomotor symptoms; Depression; Stress; Menopausal symptoms; Quality of life

MeSH Terms

Anxiety
Cross-Sectional Studies
Depression*
Female
Health Behavior
Health Promotion
Humans
Menopause
Prevalence
Prospective Studies
Psychology
Quality of Life*
World Health Organization
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