Korean J Clin Oncol.  2016 Dec;12(2):136-139. 10.14216/kjco.160123.

Gastric carcinosarcoma

Affiliations
  • 1Department of Surgery, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Korea. 20090445@kuh.ac.kr
  • 2Department of Pathology, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Korea.
  • 3Department of Internal Medicine, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Korea.
  • 4Department of Surgery, Soonchunhyang University Bucheon Hospital, Soonchunhyang University College of Medicine, Bucheon, Korea.

Abstract

Gastric carcinosarcoma is an uncommon biphasic malignant tumor. We report the case of 59-year-old man with a history of melena and dizziness. Endoscopic findings showed a fungating mass that originated from the posterior wall of upper body. Radical total gastrectomy with Roux-en-Y esophagojejunostomy was performed. In the resected specimen, immunohistochemical studies for epithelial and mesenchymal markers showed positive reactions. The mass invaded the submucosa without regional lymph node metastasis. Adjuvant chemotherapy with TS-1 (Taiho Pharmaceutical Co. Ltd, Japan) was performed after surgery despite early clinical stage due to aggressive features of carcinosarcoma.

Keyword

Carcinosarcoma; Pathology; Prognosis; Stomach

MeSH Terms

Carcinosarcoma*
Chemotherapy, Adjuvant
Dizziness
Gastrectomy
Humans
Lymph Nodes
Melena
Middle Aged
Neoplasm Metastasis
Pathology
Prognosis
Stomach
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