J Korean Soc Radiol.  2017 Feb;76(2):152-157. 10.3348/jksr.2017.76.2.152.

Fibrous Hamartoma of Infancy in the Scrotum: A Case Report

Affiliations
  • 1Department of Radiology, Eulji University Hospital, Daejeon, Korea.
  • 2Department of Pathology, Eulji University Hospital, Daejeon, Korea. kskim@eulji.ac.kr

Abstract

Fibrous hamartoma of infancy (FHI) is a rare, benign subcutaneous tumor occurring mainly before the age of 2 years. The most commonly reported locations of FHI are the extremities such as the shoulder or axilla. However, FHI arising in the genital area is extremely rare and has not been reported with correlated radiologic findings. In this case report, we present a case of 5-month-old male child diagnosed with FHI in the scrotum, with a focus on the correlation between the radiologic and pathologic findings.


MeSH Terms

Axilla
Child
Extremities
Genital Neoplasms, Male
Hamartoma*
Humans
Infant
Male
Scrotum*
Shoulder
Soft Tissue Neoplasms

Figure

  • Fig. 1 A 5-month-old boy with fibrous hamartoma of infancy; sonographic evaluation of the tumor in the right scrotum. A. Transverse scan shows a relatively ill-defined, elliptical shaped, enlarged, multi-layered, heterogeneously hyperechogenic solid mass (arrow) compared to the surrounding subcutaneous fat, measuring approximately 1.0 × 0.4 × 0.8 cm in dimensions, which does not contain calcification or necrosis. B. Inferior to the mass, the right testis (arrow) is found without any connection with the mass. The mass shows hyperechogenicity compared to the testis. C. On Doppler image, the lesion reveals scanty internal vascularity but it is surrounded by feeding vessels.

  • Fig. 2 A 5-month-old boy with fibrous hamartoma of infancy; contrast enhanced CT evaluation of the abdomen. A. On axial scan, pre contrast enhanced abdominal CT shows a well-defined mass with internal mottled fat components (arrows) with fat attenuation (-59 HU) and it shows low attenuation compared to the testis. B. On axial scan, post contrast enhanced abdominal CT shows a heterogeneously enhancing mass. Feeding vessels are present in the inferomedial portion of the mass (arrow). C. On axial scan, post contrast enhanced abdominal CT shows that the spermatic cord (arrowhead) is slightly displaced posterior to the mass and it does not show a direct connection with the mass. D. Sagittal reconstruction of post contrast enhanced abdominal CT also shows that the spermatic cord (arrowhead) is displaced posteriorly.

  • Fig. 3 A 5-month-old boy with fibrous hamartoma of infancy; histopathologic evaluation of the tumor. A. On the cross-sectional view of the tumor, the cut surface is white tan and homogenous. B. A photomicrograph shows the extent of the mass below the dermis (below the dotted line) (hematoxylin & eosin, × 12.5). C. High magnification view of the photomicrograph shows mature adipose tissue (arrowhead), spindle shaped fibroblastic cells in the collagenous stroma (arrow) and immature round mesenchymal cells (hematoxylin & eosin, × 100). D. Immunohistochemical staining shows a positive CD34 reaction in the mesenchymal cells, which indicates the presence of immature mesenchymal cells (CD34 stain, × 100).


Reference

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