Chonnam Med J.  2017 Jan;53(1):81-82. 10.4068/cmj.2017.53.1.81.

A Case of Acute Tubulointerstitial Nephritis Associated with Rifampin Therapy Presenting as Fanconi-like Syndrome

Affiliations
  • 1Department of Internal Medicine, Research Institute of Clinical Medicine, Chonbuk National University Medical School, Jeonju, Korea. kpkang@chonbuk.ac.kr

Abstract

No abstract available.


MeSH Terms

Nephritis, Interstitial*
Rifampin*
Rifampin

Figure

  • FIG. 1 Renal pathologic findings. Most glomeruli show slight mesangial matrix expansion with a mild increase in mesangial cells. The tubules show focal atrophy, degenerative changes and sloughing, with frequent infiltration of lymphocytes to form tubulitis. The interstitium is markedly widened by focal edema, fibrosis and diffuse infiltration of lymphocytes, plasma cells, neutrophils and macrophages. A small number of eosinophils are recognized (periodic acid-Schiff stain, A: original magnification ×100, B: original magnification ×400).


Reference

1. Covic A, Goldsmith DJ, Segall L, Stoicescu C, Lungu S, Volovat C, et al. Rifampicin-induced acute renal failure: a series of 60 patients. Nephrol Dial Transplant. 1998; 13:924–929.
Article
2. Nessi R, Bonoldi GL, Redaelli B, di Filippo G. Acute renal failure after rifampicin: a case report and survey of the literature. Nephron. 1976; 16:148–159.
Article
3. Schubert C, Bates WD, Moosa MR. Acute tubulointerstitial nephritis related to antituberculous drug therapy. Clin Nephrol. 2010; 73:413–419.
Article
4. Min HK, Kim EO, Lee SJ, Chang YK, Suh KS, Yang CW, et al. Rifampin-associated tubulointersititial nephritis and Fanconi syndrome presenting as hypokalemic paralysis. BMC Nephrol. 2013; 14:13.
Article
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