Clin Exp Vaccine Res.  2017 Jan;6(1):22-30. 10.7774/cevr.2017.6.1.22.

Tetanus–diphtheria–acellular pertussis vaccination for adults: an update

• Lee HJ
• Choi JH

• KMID: 2366888
• DOI: http://doi.org/10.7774/cevr.2017.6.1.22

Abstract

Although tetanus and diphtheria have become rare in developed countries, pertussis is still endemic in some developed countries. These are vaccine-preventable diseases and vaccination for adults is important to prevent the outbreak of disease. Strategies for tetanus, diphtheria, and pertussis vaccines vary from country to country. Each country needs to monitor consistently epidemiology of the diseases and changes vaccination policies accordingly. Recent studies showed that tetanus-diphtheria-acellular pertussis vaccine for adults is effective and safe to prevent pertussis disease in infants. However, vaccine coverage still remains low than expected and seroprevalence of protective antibodies levels for tetanus, diphtheria, and pertussis decline with aging. The importance of tetanus-diphtheria-acellular pertussis vaccine administration should be emphasized for the protection of young adult and elderly people also, not limited to children.

Keyword

Whooping cough; Diphtheria; Tetanus; Diphtheria-tetanus-acellular pertussis vaccines; Adult

MeSH Terms

Adult*
Aged
Aging
Antibodies
Child
Developed Countries
Diphtheria
Diphtheria-Tetanus-acellular Pertussis Vaccines
Epidemiology
Humans
Infant
Pertussis Vaccine
Seroepidemiologic Studies
Tetanus
Vaccination*
Vaccines
Whooping Cough*
Young Adult
Antibodies
Diphtheria-Tetanus-acellular Pertussis Vaccines
Pertussis Vaccine
Vaccines