Clin Orthop Surg.
2016 Mar;8(1):1-8. 10.4055/cios.2016.8.1.1.
Stem Cell Therapy for the Treatment of Hip Osteonecrosis: A 30-Year Review of Progress
- Affiliations
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- 1Department of Orthopaedic Surgery, University Paris East (UPEC), Hopital Henri Mondor, Creteil, France. philippe.hernigou@wanadoo.fr
- 2EFS Cell Therapy Facility, University Paris East (UPEC), Hopital Henri Mondor, Creteil, France.
- KMID: 2363939
- DOI: http://doi.org/10.4055/cios.2016.8.1.1
Abstract
- Avascular necrosis of the femoral head is caused by a multitude of etiologic factors and is associated with collapse with a risk of hip arthroplasty in younger populations. A focus on early disease management with the use of stem cells was proposed as early as 1985 by the senior author (PH). We undertook a systematic review of the medical literature to examine the progress in cell therapy during the last 30 years for the treatment of early stage osteonecrosis.
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