Korean J Ophthalmol.  2015 Oct;29(5):357-358. 10.3341/kjo.2015.29.5.357.

Optic Disc Edema Responding to Localized Anti-vascular Endothelial Growth Factor Treatment in a Patient with POEMS Syndrome

• Song HB
• Yu HG

• KMID: 2363813
• DOI: http://doi.org/10.3341/kjo.2015.29.5.357

Abstract

No abstract available.

MeSH Terms

Angiogenesis Inhibitors/administration & dosage
Bevacizumab/*administration & dosage
Follow-Up Studies
Humans
Intravitreal Injections
Male
Middle Aged
Optic Disk/*pathology
POEMS Syndrome/*complications/diagnosis
Papilledema/diagnosis/*drug therapy/etiology
Tomography, Optical Coherence
Vascular Endothelial Growth Factor A/*antagonists & inhibitors
Angiogenesis Inhibitors
Bevacizumab
Vascular Endothelial Growth Factor A

Figure

• 

  Fig. 1 (A-F) Initial evaluation with color photos (B,D) and optical coherence tomography (C,E) revealed optic disc edema (ODE) in the right eye (B,C) and in the left eye (D,E). Fluorescein angiography demonstrated prominent leakage in the right eye (A) and in the left eye (F). (G-L) Two months after completion of three monthly injections of intravitreal bevacizumab in the left eye, ODE and leakage were decreased in the left eye (J-L) and remained unchanged in the right eye (G-I). Eight months after completion of three monthly injections of intravitreal bevacizumab in the left eye, ODE and disc leakage were decreased in the right eye (M-O) and no definite ODE or leakage was observed in the left eye (P-R).

Reference

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