Korean J Sports Med.  2016 Jun;34(1):1-9. 10.5763/kjsm.2016.34.1.1.

Regenerative Medicine in the Treatment of Sports Injuries: Prolotherapy and Extracorporeal Shock Wave Therapy

  • 1Department of Rehabilitation Medicine, Catholic University of Daegu School of Medicine, Daegu, Korea. coolkwon@cu.ac.kr


The treatment of sports injuries traditionally has included the use of the PRICE principle (protection, rest, ice/cold, compression, and elevation), analgesics/nonsteroidal anti-inflammatory drugs (NSAIDs), and, commonly, corticosteroids. Although NSAIDs, modalities, and corticosteroids may be helpful for short-term pain reduction and early recovery of function, they do not typically reverse the structural changes associated with degenerative conditions and may contribute to even worse long-term outcomes by potentially interfering with tissue healing. Regenerative interventions, including prolotherapy and extracorporeal shock wave therapy, recently have been used to treat refractory painful conditions such as chronic tendinopathies because of the potential of these interventions to facilitate tissue healing. The true utility of prolotherapy and regenerative medicine for sports injuries will become clearer as more high-quality research is published.


Prolotherapy; Extracorporeal shockwave; Sports; Injuries; Wound healing
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