Ann Dermatol.  1997 Apr;9(2):147-150. 10.5021/ad.1997.9.2.147.

A Case of Atypical Lupus Vulgaris Developing at a Skin Graft Site

Abstract

Lupus vulgaris is most prevalent on exposed parts, especially the face but can also develop on exetremities. Lupus vulgaris originates from tuberculosis elsewhere in the body by hematogenous, lymphatic, or contiguous spread. A 19-year-old male patient came to our department. The patient had had many recurrent oozing and verrucous plaques and crusts on the left foot for one year. A skin biopsy from the lesion on the left dorsum of the foot showed scattered well defined granulomas consisting of the epithelioid cell clusters with Langerhans and foreign body type giant cells in the mid dermis. Caseation necrosis was slight. There were no bacilli on AFB staining. The multi test CMI for tuberculin was highly positive. A chest X-ray did not show any abnormal findings. The presence of Mycobacterium tuberculosis DNA was demonstrated by polymerase chain reactions (PCR) for detection of mycobacterial DNA from a routinely prepared paraffin-embedded skin specimen. Herein we report a very atypical case of lupus vulgaris confirmed by PCR.

Keyword

Atypical lupus vulgaris; PCR Skin graft

MeSH Terms

Biopsy
Dermis
DNA
Epithelioid Cells
Foot
Giant Cells, Foreign-Body
Granuloma
Humans
Lupus Vulgaris*
Male
Mycobacterium tuberculosis
Necrosis
Polymerase Chain Reaction
Skin*
Thorax
Transplants*
Tuberculin
Tuberculosis
Young Adult
DNA
Tuberculin
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