Korean J Ophthalmol.  2015 Feb;29(1):70-72. 10.3341/kjo.2015.29.1.70.

Successful Treatment of Orbital Lymphangioma with Intralesional Bleomycin and Application of Continuous Negative Pressure

Affiliations
  • 1Institute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Korea. yoonjs@yuhs.ac
  • 2Yonsei University College of Medicine, Seoul, Korea.

Abstract

No abstract available.


MeSH Terms

Antibiotics, Antineoplastic/administration & dosage
Bleomycin/*administration & dosage
Child
Dose-Response Relationship, Drug
Humans
Injections, Intralesional
Lymphangioma/diagnosis/*therapy
Magnetic Resonance Imaging
Male
Orbital Neoplasms/diagnosis/*therapy
Pressure
Tomography, X-Ray Computed
Antibiotics, Antineoplastic
Bleomycin

Figure

  • Fig. 1 Images of the 8-year-old male patient admitted for macrocystic lymphangioma in the left orbit and imaging studies of the lesion. (A,B) Images of the patient on his first clinical visit presenting with swelling of the eyelid and conjunctiva, hyperemia and severe proptosis of the left eye. Computed tomography (C) and magnetic resonance T2 weighted (D) images of the lesion during the first clinical visit. A macrocystic lymphangioma (22.2 × 25.4 mm) was observed at the inferotemporal corner of the left orbit. (E) The lesion was approached via incision into the inferior lower eyelid and exposure of the cyst interior using Sewall retractor. Bleomycin (1 IU per milliliter saline) was injected inside the cystic wall. (F) Barovac was inserted inside the cyst to maintain continuous negative pressure. (G,H) Images taken during the follow-up one month after the surgery. The patient is symptom-free and is without any sign of local recurrence. (I,J) Computed tomography and magnetic resonance images during the follow-up one months after the surgery showed nearly absorved macrocystic lymphangioma. Informed consent was received from parents of the patient.


Reference

1. Saha K, Leatherbarrow B. Orbital lymphangiomas: a review of management strategies. Curr Opin Ophthalmol. 2012; 23:433–438.
2. Wiegand S, Eivazi B, Zimmermann AP, et al. Sclerotherapy of lymphangiomas of the head and neck. Head Neck. 2011; 33:1649–1655.
3. Yoon JS, Choi JB, Kim SJ, Lee SY. Intralesional injection of OK-432 for vision-threatening orbital lymphangioma. Graefes Arch Clin Exp Ophthalmol. 2007; 245:1031–1035.
4. Acevedo JL, Shah RK, Brietzke SE. Nonsurgical therapies for lymphangiomas: a systematic review. Otolaryngol Head Neck Surg. 2008; 138:418–424.
5. Gooding C, Meyer D. Intralesional bleomycin: a potential treatment for refractory orbital lymphangiomas. Ophthal Plast Reconstr Surg. 2014; 30:e65–e67.
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