Ann Dermatol.  1999 Apr;11(2):94-97. 10.5021/ad.1999.11.2.94.

A Case of Trichoblastic Fibroma

Abstract

Trichoblastic fibroma is a rare, benign trichogenic tumor that has both an epithelial and mesenchymal component. This tumor may be confused clinically and/or histologically with basal cell carcinoma and other tumors with hair follicle differentiation. We describe here a patient with trichoblastic fibroma on the nose. For further characterization of the tumor, we studied the bcl-2 expression in this case and compared it with those of trichoepitheliomas and basal cell carcinomas. The bcl-2 expression in this case and trichoepitheliomas were positive at the periphery of the tumor nest only, whereas those of basal cell carcinomas were positive diffusely throughout the tumor nest.

Keyword

Trichogenic tumor; Trichoblastic fibroma; bcl-2

MeSH Terms

Carcinoma, Basal Cell
Fibroma*
Hair Follicle
Humans
Nose
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