J Korean Ophthalmol Soc.  2016 Nov;57(11):1806-1811. 10.3341/jkos.2016.57.11.1806.

A Case of Bilateral Branch Retinal Vein Occlusion after Taking Tamoxifen

Affiliations
  • 1Department of Ophthalmology, Maryknoll Medical Center, Busan, Korea. pjm1438@hanmail.net
  • 2Department of Ophthalmology, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea.

Abstract

PURPOSE
To report a case of bilateral branch retinal vein occlusion development after taking long-term tamoxifen adjuvant therapy. CASE SUMMARY: A 72-year-old female breast cancer patient with a 10-year history of tamoxifen intake presented with decreased visual acuity that began 5 years prior. The patient had no other past history. The best corrected visual acuity (BCVA) was 0.3 in the right eye and 0.04 in the left eye. There was no specific finding of anterior segment on slit lamp examination. On fundus examination, sheathed branch retinal veins were observed in the inferotemporal area of the right eye and superotemporal and inferotemporal areas of the left eye. Microangiopathies were observed around the occluded branch retinal veins in both eyes and macular edema was present in the left eye. Laser photocoagulation was performed at the non-perfusion area in both eyes and an intravitreal injection of bevacizumab and 3 intravitreal injections of triamcinolone were administered into the left eye. The BCVA did not change after 3 years and remained relatively stable.
CONCLUSIONS
If a patient presents with decreased visual acuity after taking tamoxifen, fundus examination and fluorescein angiogram should be performed due to the possibility of branch retinal vein occlusion.

Keyword

Bilateral branch retinal vein occlusion; Breast cancer; Tamoxifen

MeSH Terms

Aged
Bevacizumab
Breast Neoplasms
Female
Fluorescein
Humans
Intravitreal Injections
Light Coagulation
Macular Edema
Retinal Vein Occlusion*
Retinal Vein*
Retinaldehyde*
Slit Lamp
Tamoxifen*
Triamcinolone
Visual Acuity
Bevacizumab
Fluorescein
Retinaldehyde
Tamoxifen
Triamcinolone
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