Korean J Schizophr Res.  2016 Oct;19(2):68-77. 10.16946/kjsr.2016.19.2.68.

Prescription Pattern of Atypical Antipsychotics in a University Psychiatric Ward : 11-Year Observational Study

Affiliations
  • 1Department of Neuropsychiatry, Seoul National University Hospital, Seoul, Korea.
  • 2Department of Neuropsychiatry, Seoul National University Bundang Hospital, Seongnam, Korea. euitae.kim@gmail.com

Abstract


OBJECTIVES
This study investigated the prescribing patterns of atypical antipsychotics for the various psychiatric disorders in the psychiatric ward of a University hospital.
METHODS
We reviewed the medical records of patients who were discharged from an open psychiatric ward from May, 2003 through April, 2014. The association between psychiatric disorders and prescription pattern of atypical antipsychotics was analyzed.
RESULTS
The study included 3091 patients' prescription of psychiatric medication. 60% of prescription included antipsychotics; quetiapine was the most frequently prescribed antipsychotics, but the average dosage was the lowest among all the atypical antipsychotics. According to the diagnoses, prescription rates and dosage of antipsychotics were different. Prescription rates of antipsychotics were the lowest in patients with anxiety disorders, and the mean dosage were the lowest in those with delirium, dementia, and amnestic and other cognitive disorders.
CONCLUSION
This observational study shows prescription patterns of atypical antipsychotics for the treatment of psychiatric disorders in a University hospital; atypical antipsychotics were widely used for the treatment of the various disorders, and there were differences in prescription patterns for each disorders. The results of this study may be used to identify the proper atypical antipsychotics effective on certain psychiatric disorders and to propose expanding the indications of each atypical antipsychotics in the future.

Keyword

Atypical antipsychotics; Prescription pattern; Psychiatric ward; Off-label
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