J Rheum Dis.  2016 Oct;23(5):321-325. 10.4078/jrd.2016.23.5.321.

A Case of Infectious Arthritis due to Staphylococcus lugdunensis in Seronegative Rheumatoid Arthritis, Diabetes Mellitus Patient, after Intraarticular Hyaluronic Acid Injection

• Choi JW
• Yun YS
• Doo YJ
• Kim KJ
• Kim JW
• Oh JM

• KMID: 2356488
• DOI: http://doi.org/10.4078/jrd.2016.23.5.321

Abstract

Intra-articular hyaluronic acid injections for symptomatic treatment of osteoarthritis are widely used but can result in complications, such as infectious arthritis. Staphylococcus lugdunensis is a common normal skin flora but can cause severe infectious disease, such as infective endocarditis. We present the first report of infectious arthritis caused by methicillin-sensitive S. lugdunensis after intra-articular hyaluronic acid injection in an immunocompromised patient in Korea.

Keyword

Infectious arthritis; Staphylococcus lugdunensis

MeSH Terms

Arthritis, Infectious*
Arthritis, Rheumatoid*
Communicable Diseases
Diabetes Mellitus*
Endocarditis
Humans
Hyaluronic Acid*
Immunocompromised Host
Korea
Osteoarthritis
Skin
Staphylococcus lugdunensis*
Staphylococcus*
Hyaluronic Acid

Figure

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  Figure 1. The patient's clinical course was improved after antibiotics treatment. WBC: white blood cell, CRP: C-reactive protein, d: day, mo: month.

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  Figure 2. (A) The anteroposterior view of both knee. (B) The lateral view of right knee. Marginal spurs and mild subchondral sclerosis in medial femo-rotibial (black arrow) & patellofemoral compartments at right knee joint. Marginal erosion and juxtaarticular osteoporosis at lateral tibial plateau are noted in the right knee joint with large amount effusion (white arrow).

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