J Cerebrovasc Endovasc Neurosurg.  2016 Sep;18(3):286-290. 10.7461/jcen.2016.18.3.286.

Multiple Spontaneous Intracerebral Hematoma without Presenting Risk Factors

  • 1Department of Pediatric Neurosurgery, Severance Children's Hospital, Yonsei College of Medicine, Seoul, Korea. shimkyuwon@yuhs.ac


The incidence of intracerebral hemorrhage in those aged 45-84 years is 0.3-0.5%. In people over 80 years of age, this incidence increases 25-fold compared with that of the total population. The most common causes of spontaneous intracerebral hemorrhage in the younger population are vascular malformation, aneurysm, and overuse of drugs. In contrast, common causes in the elderly include hypertension, tumors, and coagulation disorders. Here, we present a case involving a 72-year-old male patient who, without any of these predisposing conditions, was admitted to the hospital with spontaneous intracerebral hemorrhage and showed signs of multifocal intracerebral hemorrhage during his stay. We conclude that spontaneous intracerebral hemorrhage can occur without any predisposing factors, and can lead to a patient's death. Therefore, the possibility of recurrent spontaneous intracerebral hemorrhage must be considered in patients with primary spontaneous intracerebral hemorrhage.


Anticardiolipin antibodies; Autoimmune disease; Intracerebral hemorrhage
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