J Korean Soc Radiol.  2016 Oct;75(4):300-303. 10.3348/jksr.2016.75.4.300.

A Case of Primary Bilateral Angiosarcoma of the Breast

• Lee K
• Kim YS
• Oh H
• Yoon E
• Lee M

• KMID: 2353681
• DOI: http://doi.org/10.3348/jksr.2016.75.4.300

Abstract

Angiosarcoma is a malignant tumor of endovascular origin that can occur in any part of the body including the breast; however, angiosarcoma of the breast is quite rare. There are two sub-types of breast angiosarcoma. One of the subtypes, primary breast angiosarcoma, is very rare; only a few cases have been reported to date. Bilateral primary breast angiosarcoma is even rarer, and several cases have been reported in postmenopausal women. We report a case of a 34-year-old woman with primary bilateral angiosarcoma. She had no other significant medical history, such as breast surgery or radiotherapy, which can lead to secondary angiosarcoma of the breast.

MeSH Terms

Adult
Breast Neoplasms
Breast*
Female
Hemangiosarcoma*
Humans
Magnetic Resonance Imaging
Mammography
Radiotherapy

Figure

• 

  Fig. 1 A 34-year-old woman with primary bilateral angiosarcoma of the breast presenting with a palpable mass in the right breast. A. Ultrasonography shows a circumscribed hypoechoic mass at the 12 o'clock position in the right breast. B. On a color Doppler image, no increased vascularity is apparent around or within the mass. C. Axial contrast-enhanced T1 fat suppression magnetic resonance imaging (MRI) shows an irregular mass in the upper central portion of the right breast (60s after gadolinium injection). Multiple unenhanced portions are apparent in the mass. D. The lower level of the axial contrast-enhanced T1 fat suppression MRI scan shows a 9 mm enhancing oval shaped mass (arrow) in the lateral portion of the left breast. E. Tumor cells show immunoreactivity for CD34, CD31, and actin, but not for S-100 (400 × magnification).

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