Clin Exp Reprod Med.  2016 Sep;43(3):139-145. 10.5653/cerm.2016.43.3.139.

The meaning of anti-Müllerian hormone levels in patients at a high risk of poor ovarian response

Affiliations
  • 1Department of Obstetrics and Gynecology, CHA Gumi Medical Center, Gumi, Korea.
  • 2Department of Obstetrics and Gynecology, Fertility Center of CHA Gangnam Medical Center, CHA University, Seoul, Korea. wooslee@cha.ac.kr

Abstract

Measurements of ovarian reserve play an important role in predicting the clinical results of assisted reproductive technology (ART). The ideal markers of ovarian reserve for clinical applications should have high specificity in order to determine genuine poor responders. Basal follicle-stimulating hormone levels, antral follicle count, and serum anti-Müllerian hormone (AMH) levels have been suggested as ovarian reserve tests that may fulfill this requirement, with serum AMH levels being the most promising parameter. Serum AMH levels have been suggested to be a predictor of clinical pregnancy in ART for older women, who are at a high risk for decreased ovarian response. We reviewed the prognostic significance of ovarian reserve tests for patients undergoing ART treatment, with a particular focus on the significance of serum AMH levels in patients at a high risk of poor ovarian response.

Keyword

Anti-Müllerian hormone; Fertilization in vitro; Infertility; Pregnancy rate

MeSH Terms

Female
Fertilization in Vitro
Follicle Stimulating Hormone
Humans
Infertility
Ovarian Reserve
Pregnancy
Pregnancy Rate
Reproductive Techniques, Assisted
Sensitivity and Specificity
Follicle Stimulating Hormone
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