Ann Dermatol.  2015 Jun;27(3):349-351. 10.5021/ad.2015.27.3.349.

Infantile Scabies Masquerading as Langerhans Cell Histiocytosis

Affiliations
  • 1Department of Dermatology, Hallym University College of Medicine, Seoul, Korea. dermap@hanmail.net

Abstract

No abstract available.


MeSH Terms

Histiocytosis, Langerhans-Cell*
Scabies*

Figure

  • Fig. 1 (A) The patient had several erythematous to brownish papules and nodules on her trunk on the initial visit. (B) Scales and erythematous patches on the palm of the patient after 1 month from the initial visit.

  • Fig. 2 (A) The dermal infiltration was composed of Langerhans cells admixed with lymphocytes and eosinophils (H&E stain, ×200). (B, C) Immunophenotyping demonstrated the majority of the histiocytic cells to be S-100 (B, ×40) and CD1a (C, ×100) positive. (D) Under dermoscopic magnification, a hangliderlike triangle indicating the scabies mites' head (arrow) was observed in the patient's palm.


Reference

1. Chosidow O. Scabies and pediculosis. Lancet. 2000; 355:819–826.
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2. Hicks MI, Elston DM. Scabies. Dermatol Ther. 2009; 22:279–292.
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3. Peterson CM, Eichenfield LF. Scabies. Pediatr Ann. 1996; 25:97–100.
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4. Bhattacharjee P, Glusac EJ. Langerhans cell hyperplasia in scabies: a mimic of Langerhans cell histiocytosis. J Cutan Pathol. 2007; 34:716–720.
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5. Favara BE, Jaffe R. The histopathology of Langerhans cell histiocytosis. Br J Cancer Suppl. 1994; 23:S17–S23.
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